Goat Secondary Antibodies
Biotium Desmoglein-1 (DSG1)(32-2B), CF488A conjugate, 0.1mg/mL
Recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF
Cayman Chemical VInyl-L-NIOhydrochlorIde 100mg
A potent, selective inhibitor of nNOS with Ki values for inhibition of nNOS, eNOS and iNOS of 100 nM, 12 µM and 60 µM, respectively
Jackson Immuno Research Labs Cy3-AffiniPure Goat Anti-Mouse IgM µ Chain Specific
Cy3-AffiniPure Goat Anti-Mouse IgM µ Chain Specific
Jackson Immuno Research Labs Alexa Fluor 680-AffiniPure Fab Fragment Goat Anti-Mouse IgG2c Fcγ Fragment Specific
Alexa Fluor 680-AffiniPure Fab Fragment Goat Anti-Mouse IgG2c Fcγ Fragment Specific
Abcam Goat F(ab')2 Anti-Mouse IgG - Fc (HRP), pre-adsorbed
Goat F(ab')2 Anti-Mouse IgG - Fc (HRP), pre-adsorbed
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical L-AlbIzzIIn 500mg
A non-proteinogenic amino acid and metabolite of 5-aminouracil; inhibits 4-methyleneglutaminase (IC50 = 20 mM for the peanut enzyme)
CAPRICO BIOTECHNOLOGIES INC IgM mFluor450, 4113145
The Caprico IGM mFluor450 is a monoclonal antibody conjugated to the mFluor450 fluorescent dye. It is clone 4113145 and is an immunoglobulin M (IgM) isotype. The antibody is specific for CD45R, also known as B220, and can be used to identify and analyze B lymphocytes in flow cytometry. The mFluor450 dye has an excitation maximum at 405nm and emission maximum at 450nm. This antibody is recommended for use in multicolor flow cytometry panels. Proper titration is required.
Abcam Goat Anti-Mouse IgA alpha chain (DyLight 594)
Goat Anti-Mouse IgA alpha chain (DyLight 594)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Cy5-YntrIethylamIn salt 1mg
A clickable fluorescent probe; ex/em = 650/680 nm, respectively; when peptide-conjugated, it has been used as a pH-independent fluorescent probe for the activity of lysosomal cathepsin proteases in S. typhimurium-infected and bystander BMDMs
ABclonal Technology SSRP1 Rabbit pAb
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
ABclonal Technology ASGR1 Rabbit pAb
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Cayman Chemical 15 R 19 Rhydroxy Prostagla
19(R)-Hydroxylated PGs occur in UG/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).{7578} 19(R)-Hydroxylated PGs are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.{2390} The 15(R)-hydroxy epimer of these 19-hydroxylated PGs is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated PGs is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.{1441}
Cayman Chemical BODIPY 508CholSTRyl LI
A fluorescently tagged cholesterol ester; ex/em = 480/508 nm, respectively; has been used to monitor cholesterol trafficking in isolated human monocyte-derived macrophages
![ABclonal Technology [KO Validated] Galectin 3/LGALS3 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000115071.jpg-250.jpg)
ABclonal Technology [KO Validated] Galectin 3/LGALS3 Rabbit pAb
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.